Conventional and dual competitive binding analyses of thyroxine using the Thyopac-4 kit.
نویسندگان
چکیده
A simple method is described for the simultaneous determinations of thyroxine and the effective thyroxine ratio (ETR) using a single kit of Thyopac-4. Thyopac ETR values obtained were 1.00 +/- 0.03 for normal subjects; 1.22 +/- 0.11 for hyperthyroid; 0.87 +/- 0.04 for hypothyroid; and 1.02 +/- 0.05 for pregnant women. Cases with TBG deficiency and the nephrotic syndrome indicated normal values. The value (x) was correlated significantly (gamma = + 0.961) with the free Thyopac index (y), representing a regression equation of y = 71.7x(2) - 88.4x + 24.2. Thyopac ETR was shown to be useful in differentiating normal thyroid states from abnormal, irrespective of changes in T(4)-binding globulin (TBG). Further, the T(4) value obtained simultaneously made it possible to detect changes in the TBG level by noting an inconsistent value for the effective thyroxine ratio.
منابع مشابه
Conventional and dual competitive binding analyses of thyroxine using the Thyopac - 4 kit ' SATOSHI HAMADA
sYNoPsis A simple method is described for the simultaneous determinations of thyroxine and the effective thyroxine ratio (ETR) using a single kit of Thyopac-4. Thyopac ETR values obtained were 1-00 ± 0'03 for normal subjects; 1 22 ± 0 11 for hyperthyroid; 0-87 ± 0-04 for hypothyroid; and 1 02 ± 0'05 for pregnant women. Cases with TBG deficiency and the nephrotic syndrome indicated normal values...
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عنوان ژورنال:
- Journal of clinical pathology
دوره 27 5 شماره
صفحات -
تاریخ انتشار 1974